We are not alone

This may seem like a line from a Spielberg movie, but after you will see this video you will understand why I have suddenly acquired microbiophobia.

One can do another video on normal and pathogenic flora specifically in different parts of our body (ie, upper respiratory/lower respiratory, etc). I am sure mess will get messier.

Related to this, EBCRC is developing rapid in-field diagnostic devices that will detect the presence of pathogenic organisms or chemical contamination in water in minutes.

The simple-to-use system will provide results directly to portable devices via simple electronic readouts, laptops and PDAs. The system will be based on proprietary technology, which integrates sample preparation and analysis and will be applicable for the detection of a broad range of organisms for example common water borne contaminants such as faecal coliforms, E. coli, Legionella, Cryptosporidium and Giardia. The system is highly adaptable to food, environmental and point of care applications.

8 Causes of Hair Loss in Women

There is known that the number of women begining hair loss in every city is rising. Medical experts agree that reasons for hair loss in women and men are very different! Most male hair loss based on genetic, but what is the reason for women hair loss?

1.Genetic. Women will also be hereditary hair loss. This is called Genetic baldness.

2.Excessive weight loss diet. This is one of reason for women hair loss. Many women try to loss weight by eating less, so it's difficult to have enough protein, iron, and other nutritional supply of hair follicles and lead to hair loss.

3.Hormonal disorders. Taking or stopping contraceptive pills can lead to hormonal disorders. And that leads to hair loss.

4.Pregnant after childbirth. Women in the end of pregnancy, their hair will enter the telogen. After delivery can grow new hair. Therefore, the new hair will be out of the original hair resulting in hair loss phenomenon.

5.Women's menstrual period.

6.Working pressure. The fatigue and pressure lead to stress. When people are in a state of tension, the blood circulation is changed, so our nutrients can not reach the scalp with blood.

7.Often tied or pulling hair.

8.Regular use of hot air and hair damaging chemicals.

Quercus - Stop Global Warming

The only effective conservation approach is to protect the habitat and this is an issue of climate change. You can distort the issue any way you so desire. At the end of the day, the sea ice is disappearing. Take away the habitat and the species follows shortly thereafter (or before)."

Scientists grow eggs from five-year-old girls

Scientists have grown eggs from tissue taken from five-year-old girls meaning future childhood cancer sufferers could go on to have children of their own.

There is known that children and young people who go through cancer are left infertile by the treatment in most of the cases. They are faced with having to use donated eggs and sperm or adopting to have their own family.

The problem is very difficult for children who develop cancer before they reach puberty. The eggs or sperm cannot be freeze at this time.

But we have good news! Scientists have managed to grow eggs in the lab using samples of ovarian tissue taken from girls as young as five.

Immature eggs can be removed from the tissue and grown to maturity in special culture.

The next step will be to see if they can be fertilised to create viable embryos. These could then be frozen and stored for future use or the unfertilised eggs could be frozen using the latest techniques which have proven more effective.

Around 1,500 children under 15 are diagnosed with cancer each year.750 are under the age of five.

The most common form of cancer in children is leukaemia, which affects 35 per cent, followed by brain or spinal tumours.

Research published online in the journal Fertility and Sterility revealed that a team at Hadassah Hebrew University Medical Centre in Jerusalem examined the ability to remove and preserve ovarian tissue from young female cancer patients and then retrieve, mature and freeze eggs from that tissue. 

They worked with 19 patients between the ages of five and 20. On average they were able to retrieve an average of nine eggs per patient and 34 per cent of them were successfully matured. 

"As our ability to treat childhood cancers improves, it becomes more important that those survivors are able to live rich, full lives, including the ability have children," said David Adamson, MD, President of the American Society for Reproductive Medicine.

"This research helps move us to the goal of allowing paediatric cancer survivors to become parents." 

Fertility doctors have attempted several methods to help young people going through cancer to conceive their own children. 

New flexible OLED displays are ultra-thin

UDC is saying they have produced an ultra-thin flexible OLED display. The entire thing is less than 50 micrometer! 

R.Ma from UDC says "We have chosen thin metal foils as the substrates for flexible displays because of their excellent thermal, mechanical and permeation barrier properties and good flexibility. Metal foils as thin as 25 mm have been used and planarization process has been developed. Another key challenge is to develop a flexible thin film permeation barrier. OLEDs degrade as a result of exposure to atmospheric oxygen and water. Working with Professor Wagner’s team at Princeton University, we have identified a flexible, highly impermeable barrier layer that is deposited from environmentally-friendly and inexpensive precursors in a single-chamber reactor. The lifetime of OLEDs encapsulated with the layers exceeds the industrial target of 1,000 hours and also the lifetime of conventionally sealed glass packaged OLEDs. Many materials are used in a flexible AMOLED: organic, inorganic and metallic systems."

BMW dealer upgrades from Windows to Linux

BMW, located in Markham, Ontario, used over the years a variety of Microsoft products for its information technology infrastructure. Now the auto dealership, with the help of an IT outsourcing consultant, has slipped a Linux appliance into the mix that has eliminated difficulties with viruses, incompatibility, and security.

The dealership also uses the Reynolds and Reynolds management system, which allows the service department to access inventory and parts databases. Not only that, but a separate accounting system handles financial issues and other internal operations.

"When we first approached Town and Country, they pointed out their requirement to meet BMW's corporate secure network access requirements," says John Gray of Bentor Technologies, a Canadian IT consultant. "We also had to support an open link in the customer lounge, with secure access to the Internet."

That prompted Bentor to begin looking at Linux boxes for its customers. Those customers had to have a very stable system that was not going to be cost-prohibitive when it came to support. Gray says that with Linux, Bentor found it could offer a mail server, automated backup, remote access, virtual private networking, server side anti-virus, and Web server for around $5,000.

That was good, because Bentor had found its car dealership customers really didn't want to go any higher than $7,500 for total cost of ownership in an IT infrastructure. "They didn't want to feel like they were just going to have to go back and buy, and buy, and buy," Gray says.

Sleep Headphones and Natural Sleep Secrets have cured my insomnia!

I've been having insomnia for a long time. I was always waking during the middle of the night. The problem was that after that, I had difficulty falling asleep again. 

So, I google it a few months ago hoping to find an answer to my problem. I've found this SleepPhones System(59.95$) and Natural Sleep Secrets. I've been following some guides I found in the book, but I still needed 20-30 minutes getting to sleep. After a while, I said what the hell. Let's try this Sleep Headphones for a change!

The results?
Sleep Earphones are the most fabulous headphones I have ever seen! The first night I've tried it, I managed to get a full night's sleep. 

Now my insomnia is cured! No kidding, I no longer take my nightly dose of Ambien.
I would recommend this combination of sleep headphones and Natural Sleep Secrets to anybody who wants a comfortable solution to sleeping in bulky headphones or those ear buds that hurt when you lay on your side and fall out several times a night.

If you have insomnia, consider using the Sleep Earphones System to help you fall asleep fast and the teachings in the book for sleeping through the night. You can even set your ipod alarm to play the included binaural beat track that helps you wake up!

Remember! LEAD your life, don't chase it!

Mobile phone users warned of new skin disorder caused by nickel on casing

As if there weren't enough health scares over mobile phones already, heavy users were yesterday given another reason to cut down on their habit.

It can bring you out in a rash.

Doctors claim 'mobile phone dermatitis' is a risk for those who develop an allergic reaction to the phone's nickel surface.

The British Association of Dermatologists is warning other doctors about the newly-identified allergy as it suspects many cases are going unreported or untreated.

Cases reported in journals so far include an 18-year-old U.S. man, a 19-year-old woman in Austria and a 14-year-old girl in Scotland.

The alert comes after scientists last month urged caution over mobile phone use saying it could take years for the health risks to emerge, although there is a consensus that children are likely to be more vulnerable.

Nickel allergy is the most common contact allergy in the UK and is thought to affect 30 per cent of the population, and rising.

Women have a higher risk of developing mobile phone dermatitis, as they are more likely to have been previously sensitised to the metal following an allergic reaction to nickel-coated jewellery.

Dr Graham Lowe, from the British Association of Dermatologists, said: 'If you have had a reaction to a nickel-coated belt-buckle or jewellery, for example, you are at greater risk of reacting to metal phones.

'In mobile phone dermatitis, the rash would typically occur on the cheek or ear, depending on where the metal part of the phone comes into contact with the skin.

Some patients have developed patches of eczematous dermatitis where their handsets has come in contact with their faces.

'In theory it could even occur on the fingers if you spend a lot of time texting on metal menu buttons.

'It is worth doctors bearing this condition in mind if they see a patient with a rash on the cheek or ear that cannot otherwise be explained.'

A spokesman for the GSM Association, the trade body representing mobile phone operators worldwide, said: 'The nickel content in mobile phones is regulated by an EU directive.

'Using a case or hands-free kit will minimise contact with surfaces that contain nickel.'

In a study published earlier this year, doctors in the US tested for nickel in 22 popular handsets from eight different manufacturers, and found it present in ten of them.

Dr Lionel Bercovitch, one of the study’s authors from Brown University, Rhode Island, said 'Nearly half of the phones we spot tested contained some free nickel.

'The menu buttons, decorative logos on the headsets and the metallic frames around the liquid crystal display (LCD) screens were the most common sites. Those with the more fashionable designs often have metallic accents and are more likely to contain free nickel in their casings.

'Given the widespread use of cell phones, the presence of metal in the exterior casing of these phones and the high prevalence of nickel sensitization in the population, it is not surprising that cell phones can cause allergic contact dermatitis.'

The British Association of Dermatologists advises anyone who develops a rash on their face which might be caused by prolonged mobile phone use to seek advice from their doctor.

Rebirth of Lada?

Lada is an automotive manufacturer based out of Russia. Their first vehicle was the Revolution that made its debut at the 2003 Frankfurt Motor Show. For this year's Paris Motor Show, Lada unveiled the third generation Revolution and it has turned more than a few heads.

The first Revolution was powered by a 1.6 liter engine that was able to put 215 horsepower to the ground and motivate the vehicle to 60mph in about 6.4 seconds. That was apparently not enough for the engineers so for the Revolution 3 they went with a more powerful turbocharged 2.0 liter engine that can make 245 horses. Also available is the 3.7 liter V6, borrowed from Nissan, which makes a more than sufficient 350 horsepower.

The body is mostly plastic while the chassis is made of light-weight steel. The dry weight of the vehicle is right at the 2400lbs mark. No official performance figures have been made available yet, but it's safe to say they will be close to or less than 6 seconds in the 0-60 sprint.

This year the Revolution 3 is strictly a design study with no working parts. According to Lada, next year they will have a production model at the Frankfurt Motor Show which you can expect to see on the road by early 2010.
Via : Motor Authority

Shark Blood May Slow the Spread of Cancer

Scientists in Australia have discovered antibodies in the blood of sharks that could potentially prove effective in battling cancer.

It has been discovered that the antibodies (molecules that fight disease) in sharks are extremely resilient and researchers hope that this quality can be isolated to help slow the spread of cancer, malaria, and other human diseases.

The Australian team discovered that shark antibodies were tough and able to survive in both very acidic and very alkaline settings. This is important as it means that a “shark pill” would still be effective within the very acidic environment of the human stomach.

The team found that the shark molecules can actually latch on to cancer molecules and stop them from spreading.

Associate Prof Mick Foley from Melbourne’s La Trobe University said: “The cells actually grow less than where we don’t add a shark antibody or we add a completely irrelevant shark antibody. So this indicates the shark antibody that we have is binding to those cancer cells and for some reason causing them to grow more slowly and perhaps even killing them.”

Sharks were singled out for this study because they are known to have very strong immune systems and don’t often catch infections. It is hoped that shark blood will prove effective for other diseases as well, such as malaria and rheumatoid arthritis.

Source: BBC

Photo: Flickr under a Creative Commons License

Experimental drug may block radiation damage

One dose of the early-stage experimental drug protected mice and monkeys from lethal doses of radiation. Future experiments will be conducted to see if tissues in humans can, likewise, be protected during radiation treatments and as an antidote from nuclear attacks.

Andrei V. Gudkov, who is chairperson of Cell Stress Biology within the Roswell Park Cancer Institute (Buffalo, New York, U.S.A.), was the lead researcher in the study.

The drug of interest has been named CBLB502, a polypeptide drug derived from Salmonella flagellin.

In the past and still today, radiation is a quite useful medical tool in combating diseases such as cancer by destroying cancerous cells. However, the radiation can also adversely affect healthy tissues, bone marrow, the gastrointestinal (GI) tract, and other such areas of the human body.

Because of the problems caused to normal cells, the amount and number of radiation treatments must be limited.

If this drug proves to be effective at protecting such healthy cells from radiation, it will be very important for future radiation treatments. However, other drugs have also been studied in the past, and they failed to live up to expectations.

The Gudkov team developed the drug related to the process called apoptosis. The process is the body’s natural (pre-programmed) way to stop defective cells from spreading to healthy cells. This activity called programmed cell death (PCD) occurs in all multicellular organisms.

However, apoptosis is prevented from occurring in cancer; that is, bad cells are killed but good cells are also adversely affected. Thus, it causes cancerous tumors to occur.

Gudkov and his team found that when apoptosis is prevented from occurring a pathway called “nuclear factor-KappaB” (NFKB) is also blocked.

The NFKB pathway is activated by flagellin, a protein in gut bacteria, and is normally used by apoptosis to destroy bad cells while leaving good cells alone.

Once the Gudkov team learned of the connection among apoptosis, NFKB, and flagellin, they decided to try to simulate the same pathway. Gudkov called their simulation a “tumor trick.” [Associated Press]

Consequently, they created a drug derived from the flagellin protein.

They injected the drug CBLB502 into mice and rhesus monkeys, waited from fifteen to sixty minutes, and then exposed the laboratory animals to lethal doses of radiation.

The investigators found that the drug improved survival rates, helping to protect bone marrow and the GI tract. The animals had more protection when the wait time was 60 minutes versus shorter times.

Especially important for radiation treatments for cancer patients, the drug CBLB502 did not prevent radiation from treating tumors in the mice as it protected healthy tissues.

As an added plus, the U.S. government is interested in the drug in order to protect its citizens against possible nuclear attack. Please read on for additional information. The abstract to the Gudkov paper is also included.

The U.S. Department of Defense (DoD) is especially interested in the applicability of the drug to possible nuclear attacks by terrorists.

Because of this use for biodefense, the DoD and other similar government agencies are funding the research by Gudkov.

In fact, Gudkov has founded the Cleveland, Biolab, Inc. to further develop the drug for possible introduction in the marketplace if it is found to be effective in humans and is approved for sale.

According to the Associated Press article “Drug Experiment Blocks Radiation Damage” by Lauran Neergaard, Dr. Richard Kolesnick (Memorial Sloan-Kettering Cancer Center, not associated with the study) stated, "For many years, the radiation oncology community has tried to develop radioprotectants. This new information on the mechanisms of tissue damage to the GI tract has resulted in a potentially important new drug to prevent this lethal GI syndrome after a radiation accident or potential terrorist attack."

The result of the researcher’s work is published in the April 11, 2008 issue of the journal Science. The title of the article is “An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models.”

Its authors are: Lyudmila G. Burdelya, Vadim I. Krivokrysenko, Thomas C. Tallant, Evguenia Strom, Anatoly S. Gleiberman, Damodar Gupta, Oleg V. Kurnasov, Farrel L. Fort, Andrei L. Osterman, Joseph A. DiDonato, Elena Feinstein, and Andrei V. Gudkov.

The abstract to their paper states, “The toxicity of ionizing radiation is associated with massive apoptosis in radiosensitive organs. Here, we investigate whether a drug that activates a signaling mechanism used by tumor cells to suppress apoptosis can protect healthy cells from the harmful effects of radiation.”

“We studied CBLB502, a polypeptide drug derived from Salmonella flagellin that binds to Toll-like receptor 5 (TLR5) and activates nuclear factor– B signaling. A single injection of CBLB502 before lethal total-body irradiation protected mice from both gastrointestinal and hematopoietic acute radiation syndromes and resulted in improved survival.”

“CBLB502 injected after irradiation also enhanced survival, but at lower radiation doses. It is noteworthy that the drug did not decrease tumor radiosensitivity in mouse models. CBLB502 also showed radioprotective activity in lethally irradiated rhesus monkeys. Thus, TLR5 agonists could potentially improve the therapeutic index of cancer radiotherapy and serve as biological protectants in radiation emergencies.”